Glutamate is the most common neurotransmitter in the central nervous system.īut glutamate is actually toxic to neurons. While GABA has a calming effect, glutamate stimulates. Glutamate is an excitatory relative of GABA. Illustrating the effect on dopamine and serotonin. Researchers tracked the brain pathways in mice showing Aniracetam’s mechanism of action. One study published in the European Journal of Pharmacology demonstrated the anti-anxiety effects of Aniracetam. Leading to improved mood and sociability. Aniracetam also seems to affect dopamine and serotonin receptors in the brain.And neural protection and repair due to brain injury. More glutamate means better cognition and memory. This causes the neurotransmitter glutamate to become more available in the brain. It reduces the desensitization of glutamate receptors. The main function of these metabolites is on the glutamate system in the brain. The main metabolite of Aniracetam (70-80%) is N-anisoyl-GABA and is responsible for many of its effects.Ģ-Pyrrolidinone and p-anisilic acid are additional metabolites of the drug (20-30%), both of which are also active. Aniracetam modulates AMPA receptors in the brain.How does Aniracetam Work in the Brain?Īniracetam boosts brain health and function in several ways. This may indicate its effects on dopamine and serotonin receptors in the brain. Aniracetam can reduce anxiety, depression and fear. And both are able to repair brain damage.Īniracetam has additional benefits not shared with Piracetam. Both racetams are able to improve learning and memory. īoth Aniracetam and Piracetam are cognitive enhancers. Only 0.2% or the original dose is available to the brain.
Because most of an Aniracetam dose is lost in the liver during digestion. The potency of Aniracetam seems almost counter-intuitive. But its effects don’t last as long as Piracetam. Fat-soluble molecules cross the blood-brain barrier more easily than water-soluble molecules.Īniracetam works faster in the brain after taking it than Piracetam because of its superior bioavailability to the brain. Hoffmann-La Roche AG developed Aniracetam in the late 1970’s as a derivative of Piracetam.Īniracetam is fat-soluble while Piracetam is water-soluble. But do not produce the same stimulant side effects as Ritalin or coffee from prolonged use.Īniracetam vs. As an ampakine nootropic, it helps increase attention span, alertness and boosts memory.Īmpakines tend to have a stimulant effect. And is known for its anxiolytic, or anti-anxiety effects.Īniracetam is considered to be up to 10-times more potent than Piracetam. One of the original synthetic nootropic compounds, it is known as a cognitive enhancer. It is sold as an over-the-counter, unrestricted compound in the United States. And Aniracetam is a Cholinergic compound, meaning it affects acetylcholine levels in the brain.Īniracetam is sold as a prescription drug in Europe and some of Asia under the names Ampamet, Draganon, Memodrin, Referan, and Sarpul. The racetam-class of nootropics have a pyrrolidone nucleus at their core. AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain. Aniracetam Repairs Fetal Alcohol SyndromeĪniracetam is in the racetam-family of nootropic compounds.Which can increase focus, and clarity of thought. It releases 200 – 300% more acetylcholine in the brain. Brain Energy: Aniracetam improves memory and recall.Resulting in better focus and concentration. Which boosts neural signaling by increasing the effectiveness of glutamate. Neurotransmitters: Aniracetam reduces the desensitization of glutamate (AMPA) receptors in your brain.And enhances your brain’s ability to repair damaged cell membranes. Brain Optimization: Aniracetam significantly improves brain function after traumatic brain injury including stroke (ischemia).And to relieve anxiety, depression, stress, and improve sociability. Neurohackers use Aniracetam to boost memory and learning. And as a supplement in the United States.Ī favorite racetam among the nootropics community. Aniracetam, like all racetam nootropics, has a pyrrolidone nucleus at its core.Īniracetam is sold as a prescription drug ( Ampamet, Draganon, Memodrin, Referan, Sarpul) in Europe. Aniracetam is up to 10-times more potent than the original racetam, Piracetam.Īniracetam was patented by Swiss-based pharmaceutical company F. Aniracetam has been shown to relieve depression, boost learning & memory, improve verbal fluidity, increase music listening pleasure, and make you more social.Īniracetam (1-p-anisoyl-2-pyrrolidinone) is a fat-soluble ampakine nootropic in the racetam-class of compounds.
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